Features
Required only hours from blood sample to results. Designed for easy operation & analysis. Highly specific in differentiating B*5701 from B*5702, B*5703, B*5704. Mix & Match design.
Required only hours from blood sample to results. Designed for easy operation & analysis. Highly specific in differentiating B*5701 from B*5702, B*5703, B*5704. Mix & Match design.
RT-PCR & SYBR Green-based detection method: each sample requires only 2 PCR rxns for detecting of HLA-B*5701 and Internal Control. Analysis is based on Ct values.
Some studies indicate the strong association of Human Leukocyte Antigen (HLA-B*5701) and Abacavir induced hypersensitivity reactions (HSR). Individuals that use DNA tests to determine their HLA genotypes prior to taking these drugs can reduce their risks of developing HSR significantly.
Relating to Drug: Irinotecan is a cancer therapy drug. UGT1A1 gene promoters usually have 5-8 TA repeat, most people with 6/6 TA repeat, few people are 6/7 or 7/7 TA repeat, 7 TA repeat genotypes were named for the UGT1A1*28.